NEW HUMAN STUDIES NOW AVAILABLE
Findings showed that total cholesterol, LDL cholesterol, and LDL:HDL ratio significantly improved with NAD3®. This is perhaps the most impressive human trial outcome in the last decade. In the study, subjects were given NAD3® for 12-weeks. Blood samples were taken during the morning following an overnight fasting period prior to taking NAD3® and following the 12-week program. Measurements were taken for total cholesterol, LDL cholesterol, and HDL cholesterol.
Download Clinical StudyNLRP3 (also known as the Inflammation Regulator) are intracellular sensors that detect danger signals and environmental irritants, resulting in the formation and activation of the NLRP3 inflammasome. Overstimulating cells can result in triggering inflammation throughout the body. Controlling NLRP3 is critical to healthy inflammation response and lower levels of NLRP3 have been shown to reduce the risk of Alzheimer's, Parkinson's, gout, and multiple sclerosis. NAD3 is able to boost cellular activity without overstimulating the cell allowing your body to run more efficiently.
Boosting NAD+ is crucial to cellular health. But elevating NAD+ levels is just one part of the equation. Mitochondrial capacity is measured by how much output (ATP) your cells produce. NAD3 has clinically shown to increase Mitochondrial capacity by 50% over the standard NAD+ booster. Along with boosting NAD+ levels, NAD3 activates localized mitochondrial sirtuins SIRT3, SIRT4, and SIRT5. This group of sirtuins is known to suppress the emergence of diverse age-related pathologies: hearing loss, cardiac fibrosis, and malignancy. Studies show that boosting mitochondrial function rejuvenates your cells so they start operating as if they were younger cells again.
When a cell becomes overstimulated it releases NLRP3 Inflammasomes causing it to inflame. Long term exposure can cause permanent damage to the cell compromising its integrity. The body's natural response is to release NRF-2 proteins to help reverse and regulate inflammation. As we age, our ability to protect the cell and activate the NRF-2 expression decreases. NAD3 has shown to significantly boost NRF-2 activity by 3x. Higher levels of NRF-2 can help stop cancer cells from growing and protect you from heart and neurodegenerative diseases.
Sirtuins are a family of proteins that regulate cellular health. NAD3 is shown to activate Sirtuins at a higher level than the standard NAD+ booster. The aging process is understood as the unwinding of the double helix structures of our DNA and the shortening of our telomeres as cells divide. The unwinding of the double helix exposes us to the free radicals we produce as a byproduct of our natural metabolic functions, as well as the toxins and pollutants of our environment. By activating sirtuins, we can naturally slow the cellular aging process, by performing the function of deacetylation, which protects DNA from toxins, pollutants, and free radicals while also repairing and restructuring the double helix.
Cellular irregularities occur more often than you might think. Preserving a cell's integrity is vital to healthy aging. Our bodies constantly change and this is all determined by your cells. NAD3 has been clinically shown to elevate P27 levels by 150% (over a controlled placebo). The P27 protein regulates the cell's lifecycle. Cancer cells grow quickly because their lifecycle isn't regulated like healthy cells. Higher levels of P27 protein is shown to exert more control over cancer cell growth and shortens their survival, especially in lymphoma cells.
